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Bcl-2 inhibitor A-1210477, Purity ≥98%

Cat. No.: X23-10-ZQ013

Bcl-2 inhibitor A-1210477, Purity ≥98%

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Synonym: 1668553-26-1; A-1210477; 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid; Bcl-2 inhibitor

  • MDL: MFCD28399118
  • CAS Number: 1668553-26-1
  • Compound CID: 66575373
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
A-1210477, soluble in warmed DMSO and insoluble in water and ethanol, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells. It targets Mcl-1.
Molecular Weight
850.04
Molecular Formula
C46H55N7O7S
Targets
Mcl-1: 26.2 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 3 mg/mL (3.52 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
A-1210477 can be used to assess its role in sustaining cancer cell viability and resistance to chemotherapy.
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