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Bcl-2 inhibitor UMI-77, Purity ≥98%

Cat. No.: X23-10-ZQ011

Bcl-2 inhibitor UMI-77, Purity ≥98%

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Synonym: 518303-20-3; UMI-77; UMI77; 2-[4-[(4-Bromophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid; 2-((4-((4-Bromophenyl)sulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetic acid; Bcl-2 inhibitor

  • MDL: MFCD03471890
  • CAS Number: 518303-20-3
  • Compound CID: 992586
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
UMI-77, soluble in DMSO and ethanol and insoluble in water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells. It targets Mcl-1.
Molecular Weight
468.34
Molecular Formula
C18H14BrNO5S2
Targets
Mcl-1: 490 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 92 mg/mL (196.43 mM); Water: Insoluble; Ethanol: 92 mg/mL (196.43 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
UMI-77 can be used to explore its function and therapeutic potential in cancer research.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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