Cat. No.: X23-12-YM054
BIBF0775
Synonym: 334951-90-5; (Z)-N-Ethyl-N-methyl-2-oxo-3-(phenyl((4-(piperidin-1-ylmethyl)phenyl)amino)methylene)indoline-6-carboxamide
- CAS Number: 334951-90-5
- PubChem CID: 135837779
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
BIBF0775, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway.
Molecular Formula
C31H34N4O2
Solubility
DMSO: 13 mg/mL (26.28 mM); Water: insoluble; Ethanol: 2 mg/mL (4.04 mM)
Applications
BIBF0775 can be used for its anti-cancer effects in part through the inhibition of angiogenesis, the process by which new blood vessels are formed to supply nutrients and oxygen to tumors.
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