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SD-208
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Cat. No.: X23-12-YM017

SD-208

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Synonym: 627536-09-8; SD 208; SD208; 2-(5-Chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

  • CAS Number: 627536-09-8
  • PubChem CID: 10316032
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SD-208, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets TGF-βRI (ALK5).
Molecular Weight
352.75
Molecular Formula
C17H10ClFN6
Targets
TGF-βRI (ALK5): 48 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 8 mg/mL (22.68 mM); Water: insoluble; Ethanol: insoluble
Applications
SD-208 can be used for its ability to block the downstream signaling cascade initiated by TGF-β.
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