Cat. No.: X23-12-YM007
Kartogenin
Synonym: 4727-31-5; 2-([1, 1'-Biphenyl]-4-ylcarbamoyl)benzoic acid; 2-[(4-Phenylphenyl)carbamoyl]benzoic acid; N-Biphenyl-4-yl-phthalamic acid
- CAS Number: 4727-31-5
- PubChem CID: 2826191
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Kartogenin, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets Smad4, and Smad5.
Molecular Formula
C20H15NO3
Solubility
DMSO: 54 mg/mL (170.16 mM); Water: insoluble; Ethanol: 4 mg/mL (12.6 mM)
Applications
Kartogenin can be used as a promising candidate for promoting cartilage repair and regeneration in conditions such as osteoarthritis, where cartilage degeneration is a primary pathology.
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