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LDN-212854
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Cat. No.: X23-12-YM004

LDN-212854

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Synonym: 1432597-26-6; LDN212854; LDN 212854; 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1, 5-a]pyrimidin-3-yl)quinoline

  • CAS Number: 1432597-26-6
  • PubChem CID: 60182388
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LDN-212854, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK2, ALK3, ALK4, and ALK5.
Molecular Weight
406.5
Molecular Formula
C25H22N6
Targets
ALK1: 2.4 nM; ALK2: 1.3 nM; ALK3: 85.8 nM; ALK4: 2133 nM; ALK5: 9276 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 73 mg/mL (179.59 mM); Water: insoluble; Ethanol: insoluble
Applications
LDN-212854 can be used in stem cell research due to its ability to modulate signaling pathways involved in cellular differentiation and development.
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