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JAK inhibitor BMS-911543, Purity ≥98%

Cat. No.: X23-10-ZQ362

JAK inhibitor BMS-911543, Purity ≥98%

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Synonym: BMS-911543; 1271022-90-2; BMS911543; BMS 911543; N,N-Dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide; JAK inhibitor

  • MDL: MFCD22200575
  • CAS Number: 1271022-90-2
  • Compound CID: 50922691
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BMS-911543, soluble in DMSO and ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, SET-2, and Tyk2.
Molecular Weight
432.52
Molecular Formula
C23H28N8O
Targets
JAK1: 360 nM; JAK2: 1.1 nM; JAK3: 75 nM; SET-2: 60 nM; Tyk2: 66 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 36 mg/mL (83.23 mM); Water: Insoluble; Ethanol: 22 mg/mL (50.86 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-911543 is used to explore its ability to inhibit JAK2 and its potential therapeutic applications in myeloproliferative neoplasms.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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