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JAK inhibitor Cerdulatinib, Purity ≥98%
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Cat. No.: X23-10-ZQ366

JAK inhibitor Cerdulatinib, Purity ≥98%

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Synonym: 1369761-01-2; Cerdulatinib hydrochloride; Cerdulatinib HCl; Cerdulatinib HCl salt; RVT-502 hydrochloride; Cerdulatinib (hydrochloride); JAK inhibitor

  • CAS Number: 1369761-01-2
  • Compound CID: 56960607
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Cerdulatinib, soluble in warmed DMSO and insoluble in water and ethanol, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets ARK5, MST1, AMPK, Chk1, FLT3, FLT4, Fms, GCK, ITK, JAK1, and JAK2.
Molecular Weight
482
Molecular Formula
C20H28ClN7O3S
Targets
ARK5: 4 nM; MST1: 4 nM; AMPK: 6 nM; Chk1: 42 nM; FLT3: 90 nM; FLT4: 51 nM; Fms: 5 nM; GCK: 18 nM; ITK: 194 nM; JAK1: 12 nM; JAK2: 6 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 42 mg/mL (87.14 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Cerdulatinib is used to investigate the dual inhibition of JAK and SYK kinases in the treatment of hematologic malignancies.
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