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JAK inhibitor Decernotinib, Purity ≥98%

Cat. No.: X23-10-ZQ373

JAK inhibitor Decernotinib, Purity ≥98%

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Synonym: Decernotinib; 944842-54-0; Adelatinib; VX-509; Decernotinib(VX-509); VRT-831509; Decernotinib (VX-509); JAK inhibitor

  • CAS Number: 944842-54-0
  • Compound CID: 59422203
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Product Size
2 mg; 5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Decernotinib, soluble in DMSO and warmed ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK1, JAK2, JAK3, and TYK2.
Molecular Weight
392.38
Molecular Formula
C18H19F3N6O
Targets
JAK1: 11 nM; JAK1: 11 nM (Ki); JAK2: 13 nM (Ki); JAK3: 2.5 nM (Ki); TYK2: 13 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 70 mg/mL (178.39 mM); Water: Insoluble; Warmed ethanol: 18 mg/mL (45.87 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Decernotinib is used to explore its selectivity for inhibiting JAK3 and its potential benefits in treating rheumatoid arthritis.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Glycolipids
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Cyclodextrin
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Dextran
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