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JAK inhibitor Filgotinib, Purity ≥98%

Cat. No.: X23-10-ZQ375

JAK inhibitor Filgotinib, Purity ≥98%

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Synonym: 1206101-20-3; Filgotinib; GLPG0634; 1206161-97-8; N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide; JAK inhibitor

  • MDL: MFCD20527867
  • CAS Number: 1206161-97-8
  • Compound CID: 49831257
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Filgotinib, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and TYK2.
Molecular Weight
425.5
Molecular Formula
C21H23N5O3S
Targets
JAK1: 10 nM; JAK2: 28 nM; JAK3: 810 nM; TYK2: 116 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 75 mg/mL (176.26 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Filgotinib is used to investigate the inhibition of JAK1 in the treatment of inflammatory bowel diseases and rheumatoid arthritis.
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O-Glycan
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Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Cyclodextrin
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Dextran
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