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JAK inhibitor Itacitinib, Purity ≥98%

Cat. No.: X23-10-ZQ382

JAK inhibitor Itacitinib, Purity ≥98%

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Synonym: Itacitinib; 1334298-90-6; INCB039110; INCB-039110; 2-(3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl)piperidin-4-yl)azetidin-3-yl)acetonitrile; Itacitinib(INCB039110); 2-[1-[1-[3-Fluoro-2-(trifluoromethyl)pyridine-4-carbonyl]piperidin-4-yl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile; JAK inhibitor

  • CAS Number: 1334298-90-6
  • Compound CID: 53380437
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Itacitinib, soluble in DMSO and ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1.
Molecular Weight
553.51
Molecular Formula
C26H23F4N9O
Targets
JAK1
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 88 mg/mL (158.98 mM); Water: Insoluble; Ethanol: 88 mg/mL (158.98 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Itacitinib is used to investigate selective inhibition of JAK1-mediated signaling.
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O-Glycan
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Blood Group and Lewis Antigen
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Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Dextran
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