Cat. No.: X23-10-ZQ399
JAK inhibitor NS-018 maleate, Purity ≥98%
Synonym: NS-018 maleate; Ilginatinib maleate; 1354799-87-3; Ilginatinib (maleate); 8P0KTT2T1Z; UNII-8P0KTT2T1Z; (S)-N-(1-(4-Fluorophenyl)ethyl)-4-(1-methyl-1H-pyrazol-4-yl)-N'-(pyrazin-2-yl)pyridine-2,6-diamine maleate; JAK inhibitor
- CAS Number: 1354799-87-3
- Compound CID: 56599590
Product Size
1 mg; 5 mg; 10 mg; 25 mg
Properties
Description
NS-018 maleate is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.
Molecular Formula
C25H24FN7O4
Targets
JAK1: 33 nM; JAK2: 0.72 nM; JAK3: 39 nM; Tyk2: 22 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
NS-018 maleate can be used to explore selective inhibition of JAK2 and Src family kinases.
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