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JAK inhibitor NVP-BSK805 dihydrochloride, Purity ≥98%

Cat. No.: X23-10-ZQ403

JAK inhibitor NVP-BSK805 dihydrochloride, Purity ≥98%

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Synonym: NVP-BSK805 2HCl; 1942919-79-0; NVP-BSK805 dihydrochloride; NVP-BSK805 (hydrochloride); NVP-BSK805 (dihydrochloride); BSK805; BSK 805; JAK inhibitor

  • CAS Number: 1942919-79-0
  • Compound CID: 57339395
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NVP-BSK805 dihydrochloride, soluble in DMSO, water and ethanol, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets FL JAK2 wt, JAK1 JH1, JAK2 JH1, JAK2 (V617F), TYK2 JH1, and TYK2 JH1.
Molecular Weight
563.47
Molecular Formula
C27H30Cl2F2N6O
Targets
FL JAK2 wt: 0.58 nM; JAK1 JH1: 31.68 nM; JAK2 JH1: 0.48 nM; JAK2 (V617F): 0.56 nM; TYK2 JH1: 18.68 nM; TYK2 JH1: 10.76 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 104 mg/mL (184.57 mM); Water: 3 mg/mL (5.32 mM); Ethanol: 14 mg/mL (24.85 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-BSK805 dihydrochloride can be utilized to study selective inhibition of JAK2 kinase function.
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