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JAK inhibitor NVP-BSK805, Purity ≥98%

Cat. No.: X23-10-ZQ402

JAK inhibitor NVP-BSK805, Purity ≥98%

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Synonym: NVP-BSK805; 1092499-93-8; 4-(2,6-Difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine; BSK 805; 8-(3,5-Difluoro-4-(morpholinomethyl)phenyl)-2-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxaline; 8-[3,5-Difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline; JAK inhibitor

  • CAS Number: 1092499-93-8
  • Compound CID: 46398810
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NVP-BSK805 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets FL JAK2 wt, JAK1 JH1, JAK2 JH1, JAK2 (V617F), and TYK2 JH1.
Molecular Weight
563.47
Molecular Formula
C27H28F2N6O.2HCl
Targets
FL JAK2 wt: 0.58 nM; JAK1 JH1: 31.68 nM; JAK2 JH1: 0.48 nM; JAK2 (V617F): 0.56 nM; TYK2 JH1: 18.68 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-BSK805 is used to investigate selective inhibition of JAK2 activity.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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