JAK inhibitor PF-06263276, Purity ≥98%

Synonym: PF-06263276; 1421502-62-6; 86YZ7HCC8V; {2-[6-(2-Ethyl-5-fluoro-4-hydroxyphenyl)-2H-indazol-3-Yl]-3,4,6,7-tetrahydro-5H-imidazo[4,5-C]pyridin-5-Yl}[5-(piperidin-1-Yl)pyrazin-2-Yl]methanone; JAK inhibitor

CAS Number: 1421502-62-6
Compound CID: 135567296

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

PF-06263276 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.

Molecular Weight

566.63

Molecular Formula

C₃₁H₃₁FN₈O₂

Targets

JAK1: 2.2 nM; JAK2: 23.1 nM; JAK3: 59.9 nM; Tyk2: 29.7 nM

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF-06263276 can be employed to investigate inhibition of JAK kinases, particularly JAK2.