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JAK inhibitor Ruxolitinib, Purity ≥98%

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Cat. No.: X23-10-ZQ381

JAK inhibitor Ruxolitinib, Purity ≥98%

Synonym: Ruxolitinib; 941678-49-5; INCB018424; Ruxolitinib (INCB018424); (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; JAK inhibitor

MDL: MFCD12031592
CAS Number: 941678-49-5
Compound CID: 25126798

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Ruxolitinib, soluble in DMSO and ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, JAK3, and Tyk2.

Molecular Weight

306.4

Molecular Formula

C₁₇H₁₈N₆

Targets

JAK1: 3.3 nM; JAK2: 2.8 nM; JAK3: 428 nM; Tyk2: 19 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 59 mg/mL (192.57 mM); Water: Insoluble; Ethanol: 59 mg/mL (192.57 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Ruxolitinib can be applied to research associated with the inhibition of JAK1 and JAK2 signaling.

Publications

Publications (0)

Publications

Publications

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