K02288, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK6, ALK2, ALK3, ALK4, and ALK5.
K02288 has applications in studying stem cell biology as well as in developing disease models for musculoskeletal dysplasia and cancer.
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