Cat. No.: X23-12-YM020
ML347
Synonym: 1062368-49-3; ML 347; ML-347; 5-[6-(4-Methoxyphenyl)pyrazolo[1, 5-a]pyrimidin-3-yl]quinoline
- CAS Number: 1062368-49-3
- PubChem CID: 44577753
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
ML347, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK2, ALK3, and ALK6.
Molecular Formula
C22H16N4O
Targets
ALK1: 46 nM; ALK2: 32 nM; ALK3: 10.8 μM; ALK6: 9.83 μM
Solubility
DMSO: 9 mg/mL (25.53 mM); Water: insoluble; Ethanol: insoluble
Applications
ML347 can be used as a selective agonist of the melanocortin 1 receptor (MC1R).
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