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MEK inhibitor GDC-0623, Purity ≥98%
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Cat. No.: X23-10-ZQ840

MEK inhibitor GDC-0623, Purity ≥98%

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Synonym: GDC-0623; 1168091-68-6; GDC 0623; RG 7421; GDC0623; 5-((2-FLUORO-4-IODOPHENYL)AMINO)-N-(2-HYDROXYETHOXY)IMIDAZO[1,5-A]PYRIDINE-6-CARBOXAMIDE; MEK inhibitor

  • MDL: MFCD25976760
  • CAS Number: 1168091-68-6
  • Compound CID: 42642654
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GDC-0623, soluble in warmed DMSO and warmed ethanol and insoluble in water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK1.
Molecular Weight
456.21
Molecular Formula
C16H14FIN4O3
Targets
MEK1: 0.13 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 89 mg/mL (195.08 mM); Water: Insoluble; Warmed ethanol: 5 mg/mL (10.95 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC-0623 can be used to study the inhibition of MEK1/2 and analyze its effects on cellular proliferation and oncogenic pathways.
Publications
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