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MEK inhibitor GDC-0973, Purity ≥98%
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Cat. No.: X23-10-ZQ831

MEK inhibitor GDC-0973, Purity ≥98%

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Synonym: Cobimetinib; 934660-93-2; GDC-0973; XL518; Xl-518; GDC 0973; RG7420; MEK inhibitor

  • MDL: MFCD22124461
  • CAS Number: 934660-93-2
  • Compound CID: 16222096
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GDC-0973, soluble in DMSO and ethanol and insoluble in water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK1.
Molecular Weight
530.1
Molecular Formula
C21H21F3IN3O2
Targets
MEK1: 4.2 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 88 mg/mL (165.62 mM); Water: Insoluble; Ethanol: 41 mg/mL (77.17 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC-0973 (Cobimetinib) can be used for studying the inhibition of MEK1/2 in cancer research.
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