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MEK inhibitor PD184352 (CI-1040), Purity ≥98%
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Cat. No.: X23-10-ZQ850

MEK inhibitor PD184352 (CI-1040), Purity ≥98%

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Synonym: 212631-79-3; CI-1040; PD184352; PD 184352; PD-184352; 2-(2-Chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; MEK inhibitor

  • MDL: MFCD02683961
  • CAS Number: 212631-79-3
  • Compound CID: 6918454
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PD184352 (CI-1040), soluble in DMSO and ethanol and insoluble in water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK1 and MEK2.
Molecular Weight
478.7
Molecular Formula
C17H14ClF2IN2O2
Targets
MEK1: 17 nM; MEK2: 17 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 92 mg/mL (192.19 mM); Water: Insoluble; Ethanol: 13 mg/mL (27.15 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD184352 (CI-1040) can be used to examine the inhibition of MEK1/2 and its implications in oncogenic signaling pathways.
Publications
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