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MEK inhibitor PD318088, Purity ≥98%
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Cat. No.: X23-10-ZQ854

MEK inhibitor PD318088, Purity ≥98%

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Synonym: PD318088; 391210-00-7; PD-318088; 5-Bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide; PD0318088; 5-Bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide; MEK inhibitor

  • CAS Number: 391210-00-7
  • Compound CID: 10231331
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PD318088, soluble in DMSO and ethanol and insoluble in water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK1/2.
Molecular Weight
561.1
Molecular Formula
C16H13BrF3IN2O4
Targets
MEK1/2
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 105 mg/mL (187.13 mM); Water: Insoluble; Ethanol: 13 mg/mL (23.17 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD318088 can be used to investigate the inhibition of MEK1/2 in signal transduction and its effects on tumor growth.
Publications
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