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MEK inhibitor SCH772984, Purity ≥98%
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Cat. No.: X23-10-ZQ861

MEK inhibitor SCH772984, Purity ≥98%

Synonym: SCH772984; 942183-80-4; SCH-772984; (R)-1-(2-oxo-2-(4-(4-(Pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide; SCH 772984; (3R)-1-[2-oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide; MEK inhibitor

  • MDL: MFCD11878503
  • CAS Number: 942183-80-4
  • Compound CID: 24866313
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
SCH772984, soluble in warmed DMSO and insoluble in water and ethanol, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets ERK2, ERK1, and MEK1.
Molecular Weight
587.68
Molecular Formula
C33H33N9O2
Targets
ERK2: 1 nM; ERK1: 4 nM; MEK1: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 13 mg/mL (22.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SCH772984 can be utilized for the inhibition of ERK1/2, studying its role in cancer cell proliferation and survival.
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