p38-MAPK inhibitor Ralimetinib, Purity ≥98%

Synonym: Ralimetinib; 862505-00-8; LY-2228820; LY-2228820 free base; Ralimetinib ( LY2228820); 862505-00-8 (free base); p38-MAPK inhibitor

CAS Number: 862505-00-8
Compound CID: 11539025

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

MSDS

Properties

Description

Ralimetinib, soluble in warmed DMSO, warmed water and ethanol, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.

Molecular Weight

420.53

Molecular Formula

C₂₄H₂₉FN₆

Form

Lyophilized powder

Purity

Solubility

Warmed DMSO: 30 mg/mL (48.9 mM); Warmed water: 85 mg/mL (138.72 mM); Ethanol: 3 mg/mL (4.89 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Ralimetinib is investigated for its ability to inhibit p38 MAPK and its implications in treating inflammatory and oncological diseases.