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p38-MAPK inhibitor PH-797804, Purity ≥98%
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Cat. No.: X23-10-ZQ885

p38-MAPK inhibitor PH-797804, Purity ≥98%

Synonym: PH-797804; 586379-66-0; PH 797804; 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide; PH797804; 1358027-80-1; 3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxopyridin-1-yl]-N,4-dimethylbenzamide; p38-MAPK inhibitor

  • CAS Number: 586379-66-0
  • Compound CID: 22049997
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
PH-797804, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38α and p38β.
Molecular Weight
477.2
Molecular Formula
C22H19BrF2N2O3
Targets
p38α: 26 nM; p38β: 102 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 84 mg/mL (175.99 mM); Water: Insoluble; Ethanol: 6 mg/mL (12.57 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PH-797804 can be utilized in the investigation of p38 kinase inhibitors in the context of inflammation and cancer.
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