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p38-MAPK inhibitor VX-702, Purity ≥98%
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Cat. No.: X23-10-ZQ884

p38-MAPK inhibitor VX-702, Purity ≥98%

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Synonym: VX-702; 745833-23-2; 479543-46-9; VX 702; VX702; 2-(2,4-Difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide; 1-(5-Carbamoyl-6-(2,4-difluorophenyl)pyridin-2-yl)-1-(2,6-difluorophenyl)urea; p38-MAPK inhibitor

  • MDL: MFCD11616590
  • CAS Number: 479543-46-9, 745833-23-2
  • Compound CID: 10341154
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Product Size
10 mg; 25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
VX-702, soluble in DMSO and insoluble in ethanol and water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38 activation.
Molecular Weight
404.3
Molecular Formula
C19H12F4N4O2
Targets
p38 activation: 4-20 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 77 mg/mL (190.45 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
VX-702 can be used to study the effects of p38 MAP kinase inhibition in inflammatory and autoimmune diseases.
Publications
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