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p38-MAPK inhibitor Doramapimod, Purity ≥98%
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Cat. No.: X23-10-ZQ883

p38-MAPK inhibitor Doramapimod, Purity ≥98%

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Synonym: Doramapimod; 285983-48-4; BIRB-796; BIRB 796; BIRB 796 (Doramapimod); BIRB796; BIRB-796 BS; p38-MAPK inhibitor

  • MDL: MFCD09752957
  • CAS Number: 285983-48-4
  • Compound CID: 156422
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Doramapimod, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38α and p38α.
Molecular Weight
527.7
Molecular Formula
C31H37N5O3
Targets
p38α: 0.1 nM (Kd); p38α: 38 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 99 mg/mL (187.61 mM); Water: Insoluble; Ethanol: 99 mg/mL (187.61 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Doramapimod can be applied to research focused on the inhibition of p38 MAP kinase in inflammatory diseases.
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