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p38-MAPK inhibitor SB 202190, Purity ≥98%
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Cat. No.: X23-10-ZQ882

p38-MAPK inhibitor SB 202190, Purity ≥98%

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Synonym: 152121-30-7; SB 202190; SB202190; SB-202190; FHPI; 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole; p38-MAPK inhibitor

  • MDL: MFCD00941964
  • CAS Number: 152121-30-7
  • Compound CID: 5169
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Product Size
10 mg; 25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SB 202190, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38α and p38β.
Molecular Weight
331.3
Molecular Formula
C20H14N3OF
Targets
p38α: 50 nM; p38β: 100 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 62 mg/mL (187.12 mM); Water: Insoluble; Ethanol: 11 mg/mL (33.19 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SB 202190 can be utilized to explore the role of p38 MAP kinase inhibition in inflammation and cancer.
Publications
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