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p38-MAPK inhibitor Skepinone-L, Purity ≥98%
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Cat. No.: X23-10-ZQ886

p38-MAPK inhibitor Skepinone-L, Purity ≥98%

Synonym: Skepinone-L; 1221485-83-1; Skepinone L; CBS3830; CHEMBL2152944; (R)-2-((2,4-difluorophenyl)amino)-7-(2,3-dihydroxypropoxy)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one; 2-[(2,4-Difluorophenyl)amino]-7-{[(2R)-2,3-Dihydroxypropyl]oxy}-10,11-Dihydro-5H-Dibenzo[a,D][7]annulen-5-One; p38-MAPK inhibitor

  • CAS Number: 1221485-83-1
  • Compound CID: 45279963
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Product Size
2 mg; 5 mg; 10 mg; 25 mg
Price
Datasheet
MSDS
Properties
Description
Skepinone-L, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38α.
Molecular Weight
425.42
Molecular Formula
C24H21F2NO4
Targets
p38α: 5 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (190.4 mM); Water: Insoluble; Ethanol: 81 mg/mL (190.4 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Skepinone-L can be employed to explore selective inhibition of p38α MAP kinase and its role in cellular processes.
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