Cat. No.: X23-10-ZQ817
TGF-β-Smad inhibitor LDN193189 HCl, Purity ≥98%
Synonym: 1062368-62-0; LDN193189 Hydrochloride; LDN193189 HCl; LDN-193189 HCl; LDN193189 (Hydrochloride); LDN-193189 monohydrochloride; LDN-193189 hydrochloride; TGF-β-Smad inhibitor
- MDL: MFCD17392570
- CAS Number: 1062368-62-0
- Compound CID: 54613581
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
LDN193189 HCl is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation. It targets ALK2 (C2C12 cells) and ALK3 (C2C12 cells).
Molecular Formula
C25H22N6.HCl
Targets
ALK2 (C2C12 cells): 5 nM; ALK3 (C2C12 cells): 30 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
LDN193189 HCl can be used to study its inhibitory effects on BMP type I receptors and their implications in developmental and disease processes.
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