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TGF-β-Smad inhibitor RepSox, Purity ≥98%
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Cat. No.: X23-10-ZQ821

TGF-β-Smad inhibitor RepSox, Purity ≥98%

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Synonym: RepSox; 446859-33-2; 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine; ALK5 Inhibitor II; ALK5 Inhibitor; TGF-β-Smad inhibitor

  • MDL: MFCD09037561
  • CAS Number: 446859-33-2
  • Compound CID: 449054
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
RepSox, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation. It targets TGFβR1 (ALK5).
Molecular Weight
287.32
Molecular Formula
C17H13N5
Targets
TGFβR1 (ALK5): 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 49 mg/mL (170.54 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
RepSox can be used to study the inhibition of TGF-β type I receptor (ALK5) in processes such as cellular differentiation and fibrosis.
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