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p38-MAPK inhibitor TAK-715, Purity ≥98%
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Cat. No.: X23-10-ZQ887

p38-MAPK inhibitor TAK-715, Purity ≥98%

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Synonym: TAK-715; 303162-79-0; TAK 715; N-(4-(2-ethyl-4-(m-tolyl)thiazol-5-yl)pyridin-2-yl)benzamide; TAK715; R-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-Benzamide; p38-MAPK inhibitor

  • MDL: MFCD17012805
  • CAS Number: 303162-79-0
  • Compound CID: 9952773
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
TAK-715, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets ERK1, IKKβ, JNK1, and MEKK1.
Molecular Weight
399.51
Molecular Formula
C24H21N3OS
Targets
ERK1: >10 μM; IKKβ: >10 μM; JNK1: >10 μM; MEKK1: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 72 mg/mL (180.22 mM); Water: Insoluble; Ethanol: 14 mg/mL (35.04 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAK-715 can be used to study p38 MAP kinase inhibition and its effects on inflammatory disease models.
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