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p38-MAPK inhibitor Losmapimod, Purity ≥98%
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Cat. No.: X23-10-ZQ909

p38-MAPK inhibitor Losmapimod, Purity ≥98%

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Synonym: Losmapimod; 585543-15-3; GSK-AHAB; GW856553; GW856553X; GW-856553; GSKAHAB; p38-MAPK inhibitor

  • MDL: MFCD16619322
  • CAS Number: 585543-15-3
  • Compound CID: 11552706
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Losmapimod, soluble in DMSO and warmed ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38α and p38β.
Molecular Weight
383.46
Molecular Formula
C22H26FN3O2
Targets
p38α: 8.1 (pKi); p38β: 7.6 (pKi)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 72 mg/mL (187.76 mM); Water: Insoluble; Warmed ethanol: 39 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Losmapimod is applied in research targeting the inhibition of p38 MAP kinase activity and its effects on inflammatory and cardiovascular diseases.
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