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p38-MAPK inhibitor Pamapimod, Purity ≥98%
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Cat. No.: X23-10-ZQ910

p38-MAPK inhibitor Pamapimod, Purity ≥98%

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Synonym: Pamapimod; 449811-01-2; RO 4402257; R1503; PamapimodR-1503; Ro4402257; Ro-4402257; p38-MAPK inhibitor

  • MDL: MFCD25976551
  • CAS Number: 449811-01-2
  • Compound CID: 16220188
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Pamapimod, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38α MAPK and p38β MAPK.
Molecular Weight
406.38
Molecular Formula
C19H20F2N4O4
Targets
p38α MAPK: 0.014 μM; p38β MAPK: 0.48 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 70 mg/mL (172.25 mM); Water: Insoluble; Ethanol: 24 mg/mL (59.06 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pamapimod is used in studies investigating its efficacy in blocking p38 MAP kinase in the context of autoimmune and inflammatory diseases.
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