p38-MAPK inhibitor PD 169316, Purity ≥98%

Synonym: 152121-53-4; PD 169316; PD-169316; PD169316; 4-(4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl)pyridine; 4-[4-(4-Fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine; 4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole; p38-MAPK inhibitor

MDL: MFCD12405019
CAS Number: 152121-53-4
Compound CID: 4712

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

PD 169316, soluble in DMSO and insoluble in ethanol and water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates.

Molecular Weight

360.3

Molecular Formula

C₂₀H₁₃FN₄O₂

Form

Lyophilized powder

Purity

Solubility

DMSO: 12 mg/mL (33.3 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD 169316 is used to explore the selective inhibition of p38 MAP kinase and its role in cytokine production and inflammation.