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p38-MAPK inhibitor Pexmetinib, Purity ≥98%
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Cat. No.: X23-10-ZQ891

p38-MAPK inhibitor Pexmetinib, Purity ≥98%

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Synonym: Pexmetinib; 945614-12-0; ARRY-614; Pexmetinib [INN]; Pexmetinib (ARRY-614); Pexmetinib(ARRY-614); p38-MAPK inhibitor

  • CAS Number: 945614-12-0
  • Compound CID: 24765037
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Pexmetinib, soluble in DMSO and ethanol and insoluble in water, targets the ATP-binding site of the kinase, thereby preventing phosphorylation of downstream substrates. It targets p38 MAPK and Tie-2.
Molecular Weight
556.63
Molecular Formula
C31H33FN6O3
Targets
p38 MAPK; Tie-2
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 96 mg/mL (172.46 mM); Water: Insoluble; Ethanol: 96 mg/mL (172.46 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pexmetinib can be employed to explore the dual inhibition of MEK and AXL pathways in cancer treatment.
Publications
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